ADP-specific phosphofructokinase
Template:Infobox enzyme In enzymology, an ADP-specific phosphofructokinase (EC 2.7.1.146) is an enzyme that catalyzes the chemical reaction
- ADP + D-fructose 6-phosphate AMP + D-fructose 1,6-bisphosphate
Thus, the two substrates of this enzyme are ADP and D-fructose 6-phosphate, whereas its two products are AMP and D-fructose 1,6-bisphosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:D-fructose-6-phosphate 1-phosphotransferase. This enzyme is also called ADP-6-phosphofructokinase, ADP-dependent phosphofructokinase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U2X.
References
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