2,2-Dimethoxypropane

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2,2-Dimethoxypropane[1]
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Molar mass 104.15 g/mol
Appearance Colorless liquid
Density 0.85 g/cm3
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2,2-Dimethoxypropane (DMP) is an organic compound with the formula (CH3)2C(OCH3)2. A colorless liquid, it is the product of the condensation of acetone and methanol. DMP is used as a water scavenger in water-sensitive reactions. Upon acid-catalyzed reaction, DMP reacts quantitatively with water to form acetone and methanol.[2] This property can be used to accurately determine the amount of water in a sample, alternatively to the Karl Fischer method.[3]

DMP is specifically used to prepare acetonides:[4][5]

RCHOHCHOHCH2 + (MeO)2CMe2 → RCHCHCH2O2CMe2 + 2 MeOH

Dimethoxypropane is an intermediate for the synthesis of 2-methoxypropene.

In histology, DMP is used for the dehydration of animal tissue.[6]

References

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  1. ↑ 2,2-Dimethoxypropane at Sigma-Aldrich
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External links

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