1,2-Naphthoquinone

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1,2-Naphthoquinone
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1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula Template:Chem/link. This yellow solid is prepared by oxidation of 1-amino-2-hydroxynaphthalene with ferric chloride.[1]

Occurrence

This diketone (an ortho-quinone) is a metabolite of naphthalene. It arises from the naphthalene-1,2-oxide.[2]

It is also found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.[3]

See also

References

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External links

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