Triprolidine: Difference between revisions
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imported>Slothwizard m Only up to three names in trade name section allowed in infobox |
imported>TooManyFingers Moved patent date and medical use date upwards. Are those really "society and culture" material? I left that note attached to them anyway. |
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'''Triprolidine''' is an [[Over-the-counter drug|over-the-counter]] [[antihistamine]] with [[anticholinergic]] properties.<ref name="Goldsmith">{{cite journal | vauthors = Goldsmith P, Dowd PM | title = The new H1 antihistamines. Treatment of urticaria and other clinical problems | journal = Dermatologic Clinics | volume = 11 | issue = 1 | pages = 87–95 | date = January 1993 | doi = 10.1016/S0733-8635(18)30285-7 | pmid = 8094649 }}</ref> It is used to combat the symptoms associated with [[allergy|allergies]] and is sometimes combined with other [[common cold|cold]] medications designed to provide general relief for [[influenza|flu]]-like symptoms.<ref>{{cite journal | vauthors = Williams BO, Liao SH, Lai AA, Arnold JD, Perkins JG, Blum MR, Findlay JW | title = Bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products | journal = Clinical Pharmacy | volume = 3 | issue = 6 | pages = 638–43 | year = 1984 | pmid = 6509877 }}</ref> As with many antihistamines, the most common [[Adverse effect (medicine)|side effect]] is drowsiness.<ref name="Goldsmith" /> | '''Triprolidine''' is an [[Over-the-counter drug|over-the-counter]] [[antihistamine]] with [[anticholinergic]] properties.<ref name="Goldsmith">{{cite journal | vauthors = Goldsmith P, Dowd PM | title = The new H1 antihistamines. Treatment of urticaria and other clinical problems | journal = Dermatologic Clinics | volume = 11 | issue = 1 | pages = 87–95 | date = January 1993 | doi = 10.1016/S0733-8635(18)30285-7 | pmid = 8094649 }}</ref> It is used to combat the symptoms associated with [[allergy|allergies]] and is sometimes combined with other [[common cold|cold]] medications designed to provide general relief for [[influenza|flu]]-like symptoms.<ref>{{cite journal | vauthors = Williams BO, Liao SH, Lai AA, Arnold JD, Perkins JG, Blum MR, Findlay JW | title = Bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products | journal = Clinical Pharmacy | volume = 3 | issue = 6 | pages = 638–43 | year = 1984 | pmid = 6509877 }}</ref> As with many antihistamines, the most common [[Adverse effect (medicine)|side effect]] is drowsiness.<ref name="Goldsmith" /> | ||
<!-- Society and culture --> | <!-- Society and culture --> | ||
Triprolidine was patented in 1948 and came into medical use in 1953,<ref name=Fis2006>{{cite book | vauthors = Fischer J, Ganellin CR |title= Analogue-based Drug Discovery |date=2006 |publisher=John Wiley & Sons |isbn=9783527607495 |page=546 |url=https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA546 |language=en}}</ref> and has mostly been replaced in popular medications by other antihistamines including [[diphenhydramine]], [[promethazine]], [[chlorpheniramine]], as well as by [[Second generation antihistamines|second-generation antihistamines]] including [[loratadine]] and [[fexofenadine]]. Triprolidine remains an ingredient in the cold medicine [[Actifed]] in many territories.{{Citation needed|date=March 2025}} | |||
== See also == | == See also == | ||
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[[Category:1-Pyrrolidinyl compounds]] | [[Category:1-Pyrrolidinyl compounds]] | ||
[[Category:4-Tolyl compounds]] | [[Category:4-Tolyl compounds]] | ||
[[Category:Over-the-counter drugs in the United States]] | |||
Latest revision as of 15:37, 26 October 2025
Template:Short description Template:Cs1 config Script error: No such module "about". Template:Drugbox Triprolidine is an over-the-counter antihistamine with anticholinergic properties.[1] It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms.[2] As with many antihistamines, the most common side effect is drowsiness.[1]
Triprolidine was patented in 1948 and came into medical use in 1953,[3] and has mostly been replaced in popular medications by other antihistamines including diphenhydramine, promethazine, chlorpheniramine, as well as by second-generation antihistamines including loratadine and fexofenadine. Triprolidine remains an ingredient in the cold medicine Actifed in many territories.Script error: No such module "Unsubst".
See also
References
Template:Antihistamines Script error: No such module "Navbox". Template:Histamine receptor modulators Template:Muscarinic acetylcholine receptor modulators