Cephamycin: Difference between revisions
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Cephamycins possess a [[methoxy]] group at the 7-alpha position.<ref name="isbn1-55581-258-9">{{cite book |author=Oreste A. Mascaretti |title=Bacteria Versus Antibacterial Agents: An Integrated Approach |publisher=American Society Microbiology |year=2003 |pages=144 |isbn=1-55581-258-9 }}</ref> | Cephamycins possess a [[methoxy]] group at the 7-alpha position.<ref name="isbn1-55581-258-9">{{cite book |author=Oreste A. Mascaretti |title=Bacteria Versus Antibacterial Agents: An Integrated Approach |publisher=American Society Microbiology |year=2003 |pages=144 |isbn=1-55581-258-9 }}</ref> | ||
In addition, cephamycins have been shown to be stable against extended-spectrum beta-lactamase (ESBL) producing organisms, although their use in clinical practice is lacking for this indication.{{ | In addition, cephamycins have been shown to be stable against extended-spectrum beta-lactamase (ESBL) producing organisms, although their use in clinical practice is lacking for this indication.<ref>{{Cite book |last=Munoz-Price |first=L |title=Principles and Practice of Hospital Medicine |publisher=McGraw-Hill Education |year=2017 |edition=2nd |location=New York |chapter=Chapter 185: Antibiotic Resistance}}</ref> | ||
==Examples== | ==Examples== | ||
Latest revision as of 18:42, 8 July 2025
Cephamycins are a group of β-lactam antibiotics. They are very similar to cephalosporins, and the cephamycins are sometimes classified as cephalosporins.
Like cephalosporins, cephamycins are based upon the cephem nucleus. Unlike most cephalosporins, cephamycins are a very efficient antibiotic against anaerobic microbes.Script error: No such module "Unsubst".
Cephamycins were originally produced by Streptomyces, but synthetic ones have been produced as well.Script error: No such module "Unsubst".
Cephamycins possess a methoxy group at the 7-alpha position.[1]
In addition, cephamycins have been shown to be stable against extended-spectrum beta-lactamase (ESBL) producing organisms, although their use in clinical practice is lacking for this indication.[2]
Examples
Cephamycins include:
References
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