Darifenacin: Revision history

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26 May 2025

  • curprev 09:0409:04, 26 May 2025 2a09:5e41:a37:d0::1004 talk 6,503 bytes +6,503 The cut-offs are absolute, not relative. Any ligand with pKi > 7 is labelled “+++”. Darifenacin’s pKi is 9.1 at M3 but still 8.2 at M1; both exceed the cut-off, so every cell gets “+++”. The table therefore hides the 59-fold selectivity that appears when you look at Ki ratios .
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