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<p><b>New page</b></p><div>'''VectorBase'''<ref>{{cite journal |pmid=17145709 |year=2007 |last1=Lawson |first1=D |last2=Arensburger |first2=P |last3=Atkinson |first3=P |last4=Besansky |first4=NJ |last5=Bruggner |first5=RV |last6=Butler |first6=R |last7=Campbell |first7=KS |last8=Christophides |first8=GK |last9=Christley |first9=S |last10=Dialynas |first10=E. |last11=Emmert |first11=D. |last12=Hammond |first12=M. |last13=Hill |first13=C. A. |last14=Kennedy |first14=R. C. |last15=Lobo |first15=N. F. |last16=MacCallum |first16=M. R. |last17=Madey |first17=G. |last18=Megy |first18=K. |last19=Redmond |first19=S. |last20=Russo |first20=S. |last21=Severson |first21=D. W. |last22=Stinson |first22=E. O. |last23=Topalis |first23=P. |last24=Zdobnov |first24=E. M. |last25=Birney |first25=E. |last26=Gelbart |first26=W. M. |last27=Kafatos |first27=F. C. |last28=Louis |first28=C. |last29=Collins |first29=F. H. |title=VectorBase: a home for invertebrate vectors of human pathogens |volume=35 |issue=Database issue |pages=D503–5 |doi=10.1093/nar/gkl960 |pmc=1751530 |journal=Nucleic Acids Research|display-authors=8 }}</ref><ref>{{cite journal |pmid=19028744 |year=2009 |last1=Lawson |first1=D |last2=Arensburger |first2=P |last3=Atkinson |first3=P |last4=Besansky |first4=NJ |last5=Bruggner |first5=RV |last6=Butler |first6=R |last7=Campbell |first7=KS |last8=Christophides |first8=GK |last9=Christley |first9=S |last10=Dialynas |first10=E. |last11=Hammond |first11=M. |last12=Hill |first12=C. A. |last13=Konopinski |first13=N. |last14=Lobo |first14=N. F. |last15=MacCallum |first15=R. M. |last16=Madey |first16=G. |last17=Megy |first17=K. |last18=Meyer |first18=J. |last19=Redmond |first19=S. |last20=Severson |first20=D. W. |last21=Stinson |first21=E. O. |last22=Topalis |first22=P. |last23=Birney |first23=E. |last24=Gelbart |first24=W. M. |last25=Kafatos |first25=F. C. |last26=Louis |first26=C. |last27=Collins |first27=F. H. |title=VectorBase: a data resource for invertebrate vector genomics |volume=37 |issue=Database issue |pages=D583–7 |doi=10.1093/nar/gkn857 |pmc=2686483 |journal=Nucleic Acids Research|display-authors=8 }}</ref> is one of the five [[Bioinformatics Resource Centers]] (BRC) funded by the [[National Institute of Allergy and Infectious Diseases]] (NIAID), a component of the [[National Institutes of Health]] (NIH), which is an agency of the [[United States Department of Health and Human Services]]. VectorBase is focused on invertebrate vectors of [[human pathogen]]s working with the sequencing centers and the research community to curate vector genomes (mainly [[Genome project|genome annotation]]).<br />
<br />
==Genomes covered in the VectorBase database==<br />
* ''[[Aedes aegypti]]''<ref>{{cite journal |pmid=17510324 |year=2007 |last1=Nene |first1=V |last2=Wortman |first2=JR |last3=Lawson |first3=D |last4=Haas |first4=B |last5=Kodira |first5=C |last6=Tu |first6=ZJ |last7=Loftus |first7=B |last8=Xi |first8=Z |last9=Megy |first9=K |last10=Grabherr |first10=M. |last11=Ren |first11=Q. |last12=Zdobnov |first12=E. M. |last13=Lobo |first13=N. F. |last14=Campbell |first14=K. S. |last15=Brown |first15=S. E. |last16=Bonaldo |first16=M. F. |last17=Zhu |first17=J. |last18=Sinkins |first18=S. P. |last19=Hogenkamp |first19=D. G. |last20=Amedeo |first20=P. |last21=Arensburger |first21=P. |last22=Atkinson |first22=P. W. |last23=Bidwell |first23=S. |last24=Biedler |first24=J. |last25=Birney |first25=E. |last26=Bruggner |first26=R. V. |last27=Costas |first27=J. |last28=Coy |first28=M. R. |last29=Crabtree |first29=J. |last30=Crawford |first30=M. |title=Genome sequence of Aedes aegypti, a major arbovirus vector |volume=316 |issue=5832 |pages=1718–23 |doi=10.1126/science.1138878 |journal=Science |pmc=2868357|bibcode = 2007Sci...316.1718N |display-authors=8 }}</ref><br />
* ''[[Anopheles gambiae]]''<ref>{{cite journal |pmid=12364791 |year=2002 |last1=Holt |first1=RA |last2=Subramanian |first2=GM |last3=Halpern |first3=A |last4=Sutton |first4=GG |last5=Charlab |first5=R |last6=Nusskern |first6=DR |last7=Wincker |first7=P |last8=Clark |first8=AG |last9=Ribeiro |first9=JM |last10=Wides |first10=R |last11=Salzberg |first11=S. L. |last12=Loftus |first12=B |last13=Yandell |first13=M |last14=Majoros |first14=W. H. |last15=Rusch |first15=D. B. |last16=Lai |first16=Z |last17=Kraft |first17=C. L. |last18=Abril |first18=J. F. |last19=Anthouard |first19=V |last20=Arensburger |first20=P |last21=Atkinson |first21=P. W. |last22=Baden |first22=H |last23=De Berardinis |first23=V |last24=Baldwin |first24=D |last25=Benes |first25=V |last26=Biedler |first26=J |last27=Blass |first27=C |last28=Bolanos |first28=R |last29=Boscus |first29=D |last30=Barnstead |first30=M |title=The genome sequence of the malaria mosquito Anopheles gambiae |volume=298 |issue=5591 |pages=129–49 |doi=10.1126/science.1076181 |journal=Science |bibcode=2002Sci...298..129H|display-authors=8 |citeseerx=10.1.1.149.9058 |s2cid=4512225 }}</ref><br />
* ''[[Culex quinquefasciatus]]''<br />
* ''[[Ixodes scapularis]]''<br />
* ''[[Pediculus humanus]]''<br />
* ''[[Rhodnius prolixus]]''<br />
<br />
==Tools available through the VectorBase site==<br />
* Genome browser<br />
* Community annotation system<br />
* Microarray and gene expression repository<br />
* Controlled vocabularies for anatomy,<ref>{{cite journal |pmid=18237287 |year=2008 |last1=Topalis |first1=P |last2=Tzavlaki |first2=C |last3=Vestaki |first3=K |last4=Dialynas |first4=E |last5=Sonenshine |first5=DE |last6=Butler |first6=R |last7=Bruggner |first7=RV |last8=Stinson |first8=EO |last9=Collins |first9=FH |last10=Louis |first10=C. |title=Anatomical ontologies of mosquitoes and ticks, and their web browsers in VectorBase |volume=17 |issue=1 |pages=87–9 |doi=10.1111/j.1365-2583.2008.00781.x |journal=Insect Molecular Biology|s2cid=8618269 |display-authors=8 }}</ref> [[insecticide resistance]] and vector-borne diseases (malaria and dengue fever)<br />
* BLAST searches for all covered genomes<br />
<br />
==See also==<br />
* [[Vector (epidemiology)|Vectors in epidemiology]]<br />
<br />
==References==<br />
{{reflist}}<br />
<br />
==External links==<br />
* [http://www.vectorbase.org vectorbase.org]<br />
* [https://web.archive.org/web/20090420082012/http://www3.niaid.nih.gov/research/resources/brc/default.htm Bioinformatics Resource Centers] The NIAID page describing the goals and activities of the BRCs<br />
* [http://www.brc-central.org/cgi-bin/brc-central/brc_central.cgi Pathogen Portal] Hub site for the five BRCs; provides summary information<br />
;VectorBase genome browsers<br />
* [https://www.vectorbase.org/Aedes_aegypti/Info/ ''Aedes aegypti'' genome browser] at VectorBase<br />
* [https://www.vectorbase.org/Anopheles_gambiae/Info/ ''Anopheles gambiae'' genome browser] at VectorBase<br />
* [https://www.vectorbase.org/Culex_quinquefasciatus/Info/ ''Culex quinquefasciatus'' genome browser] at VectorBase<br />
* [https://www.vectorbase.org/Ixodes_scapualris/Info/ ''Ixodes scapularis'' genome browser] at VectorBase<br />
* [https://www.vectorbase.org/Pediculus_humanus/Info/ ''Pediculus humanus'' genome browser] at VectorBase<br />
* [https://www.vectorbase.org/Rhodnius_prolixus/Info/ ''Rhodnius prolixus'' genome browser] at VectorBase<br />
<br />
{{Bioinformatics}}<br />
<br />
{{authority control}}<br />
<br />
[[Category:Biological databases]]<br />
[[Category:Online databases]]<br />
[[Category:Biology websites]]<!---VectorBase browser links---><br />
[[Category:Epidemiology organizations]]</div>
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