Urease - Revision history

http://debianws.lexgopc.com/wiki143/index.php?action=history&feed=atom&title=Urease Urease - Revision history 2026-06-12T02:12:50Z Revision history for this page on the wiki MediaWiki 1.43.1 http://debianws.lexgopc.com/wiki143/index.php?title=Urease&diff=3431438&oldid=prev imported>Monkbot: Monkbot/task 21: Replace page(s) with article-number; 2025-10-04T13:30:17Z

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imported>Monkbot http://debianws.lexgopc.com/wiki143/index.php?title=Urease&diff=762881&oldid=prev imported>Amklose: Removed a stray sentence fragment. 2025-06-26T14:13:55Z

<p>Removed a stray sentence fragment.</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Previous revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 14:13, 26 June 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l12">Line 12:</td> <td colspan="2" class="diff-lineno">Line 12:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> }}</ref> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> }}</ref> </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Ureases''' ({{EC number|3.5.1.5}}), functionally, belong to the [[Protein family|superfamily]] of [[amidohydrolases]] and phosphotriesterases.<ref name="pmid9144792">{{cite journal | vauthors = Holm L, Sander C | title = An evolutionary treasure: unification of a broad set of amidohydrolases related to urease | journal = Proteins | volume = 28 | issue = 1 | pages = 72–82 | year = 1997 | pmid = 9144792 | doi = 10.1002/(SICI)1097-0134(199705)28:1<72::AID-PROT7>3.0.CO;2-L | citeseerx = 10.1.1.621.2752 | s2cid = 38845090 }}</ref> Ureases are found in numerous [[Bacteria]], [[Archaea]], [[fungi]], [[algae]], plants, and some [[invertebrates]]. Ureases are nickel-containing [[metalloenzymes]] of high molecular weight.<ref name="Krajewska">{{cite journal | vauthors = Krajewska B, van Eldik R, Brindell M | title = Temperature- and pressure-dependent stopped-flow kinetic studies of jack bean urease. Implications for the catalytic mechanism | journal = Journal of Biological Inorganic Chemistry | volume = 17 | issue = 7 | pages = 1123–1134 | date = 13 August 2012 | pmid = 22890689 | pmc = 3442171 | doi = 10.1007/s00775-012-0926-8 }}</ref> Ureases <del style="font-weight: bold; text-decoration: none;">are distinct from Urecases </del>are important in degrading avian faecal matter, which is rich in uric acid, the breakdown product of which is urea, which is then degraded by urease as described here. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Ureases''' ({{EC number|3.5.1.5}}), functionally, belong to the [[Protein family|superfamily]] of [[amidohydrolases]] and phosphotriesterases.<ref name="pmid9144792">{{cite journal | vauthors = Holm L, Sander C | title = An evolutionary treasure: unification of a broad set of amidohydrolases related to urease | journal = Proteins | volume = 28 | issue = 1 | pages = 72–82 | year = 1997 | pmid = 9144792 | doi = 10.1002/(SICI)1097-0134(199705)28:1<72::AID-PROT7>3.0.CO;2-L | citeseerx = 10.1.1.621.2752 | s2cid = 38845090 }}</ref> Ureases are found in numerous [[Bacteria]], [[Archaea]], [[fungi]], [[algae]], plants, and some [[invertebrates]]. Ureases are nickel-containing [[metalloenzymes]] of high molecular weight.<ref name="Krajewska">{{cite journal | vauthors = Krajewska B, van Eldik R, Brindell M | title = Temperature- and pressure-dependent stopped-flow kinetic studies of jack bean urease. Implications for the catalytic mechanism | journal = Journal of Biological Inorganic Chemistry | volume = 17 | issue = 7 | pages = 1123–1134 | date = 13 August 2012 | pmid = 22890689 | pmc = 3442171 | doi = 10.1007/s00775-012-0926-8 }}</ref> Ureases are important in degrading avian faecal matter, which is rich in uric acid, the breakdown product of which is urea, which is then degraded by urease as described here. </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>These [[enzyme]]s [[catalysis|catalyze]] the [[hydrolysis]] of [[urea]] into [[carbon dioxide]] and [[ammonia]]:</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>These [[enzyme]]s [[catalysis|catalyze]] the [[hydrolysis]] of [[urea]] into [[carbon dioxide]] and [[ammonia]]:</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>: (NH<sub>2</sub>)<sub>2</sub>CO + H<sub>2</sub>O {{overset|urease|→}} CO<sub>2</sub> + 2NH<sub>3</sub></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>: (NH<sub>2</sub>)<sub>2</sub>CO + H<sub>2</sub>O {{overset|urease|→}} CO<sub>2</sub> + 2NH<sub>3</sub></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>The hydrolysis of [[urea]] occurs in two stages. <del style="font-weight: bold; text-decoration: none;"> </del>In the first stage, [[ammonia]] and [[carbamic acid]] are produced. The [[carbamate]] spontaneously and rapidly hydrolyzes to [[ammonia]] and [[carbonic acid]]. Urease activity increases the [[pH]] of its environment as ammonia is produced, which is basic.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The hydrolysis of [[urea]] occurs in two stages. In the first stage, [[ammonia]] and [[carbamic acid]] are produced. The [[carbamate]] spontaneously and rapidly hydrolyzes to [[ammonia]] and [[carbonic acid]]. Urease activity increases the [[pH]] of its environment as ammonia is produced, which is basic.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== History ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== History ==</div></td></tr> </table>

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