imported>GreatSculptorIthas: Adding short description: "Patch of a protein which determines its final location in the cell" (Shortdesc helper)

2019-07-03T15:29:22Z

Adding short description: "Patch of a protein which determines its final location in the cell" (Shortdesc helper)

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{{short description|Patch of a protein which determines its final location in the cell}}
{{Unreferenced|date=December 2009}}
[[Image:protein sorting signals.png|thumb|Schematic of 4 different protein signals that enable localisation in the cell]]

A protein '''signal patch''' contains information to send a given [[protein]] to the indicated location in the [[cell (biology)|cell]]. It is made up of [[amino acid]] residues that are distant to one another in the [[primary structure|primary sequence]], but come close to each other in the [[tertiary structure]] of the folded protein (see red patch in the diagram). Signal patches, unlike some [[Signal peptide|signal sequence]]s, are not cleaved from the mature protein after sorting. They are very difficult to predict. [[Nuclear localization signal]]s are often signal patches although signal sequences also exist. They are found on proteins destined for the [[cell nucleus|nucleus]] and enable their selective transport from the cytosol into the nucleus through the nuclear pore complexes.

==See also==
* [[protein targeting]]
* [[signal peptide]]

{{Protein topics}}

{{DEFAULTSORT:Signal Patch}}
[[Category:Protein targeting]]

Signal patch - Revision history

imported>GreatSculptorIthas: Adding short description: "Patch of a protein which determines its final location in the cell" (Shortdesc helper)