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	<title>Complement component 7 - Revision history</title>
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	<updated>2026-10-25T23:44:14Z</updated>
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		<title>imported&gt;SimLibrarian at 05:30, 8 January 2024</title>
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		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Short description|Protein found in humans}}&lt;br /&gt;
{{infobox gene}}&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Complement component 7&amp;#039;&amp;#039;&amp;#039; is a [[protein]] involved in the [[complement system]] of the [[innate immune system]]. C7 is part of the [[complement membrane attack complex|membrane attack complex (MAC)]] which creates a hole on [[pathogen]] surfaces, leading to cell [[lysis]] and death.&lt;br /&gt;
&lt;br /&gt;
Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the [[cell membrane|phospholipid bilayer]] of the pathogen.&lt;br /&gt;
&lt;br /&gt;
==See also==&lt;br /&gt;
* [[Terminal complement pathway deficiency]]&lt;br /&gt;
&lt;br /&gt;
==External links==&lt;br /&gt;
* {{MeshName|Complement+C7}}&lt;br /&gt;
* {{PDBe-KB2|P10643|Human Complement component C7}}&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
{{Reflist}}&lt;br /&gt;
&lt;br /&gt;
{{Complement system}}&lt;br /&gt;
&lt;br /&gt;
[[Category:Complement system]]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{gene-5-stub}}&lt;/div&gt;</summary>
		<author><name>imported&gt;SimLibrarian</name></author>
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