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{{infobox enzyme
| Name = amino-acid racemase
| EC_number = 5.1.1.10
| CAS_number = 9068-61-5
| GO_code = 0047661
| image =
| width =
| caption =
}}
In [[enzymology]], an '''amino-acid racemase''' ({{EnzExplorer|5.1.1.10}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]

:an L-amino acid <math>\rightleftharpoons</math> a D-amino acid

Hence, this enzyme has one [[substrate (biochemistry)|substrate]], L-[[amino acid]], and one [[product (chemistry)|product]], D-[[amino acid]].

This enzyme belongs to the family of [[isomerase]]s, specifically those [[racemase]]s and [[epimerase]]s acting on [[amino acid]]s and derivatives. The [[List of enzymes|systematic name]] of this enzyme class is '''amino-acid racemase'''. This enzyme is also called '''L-amino acid racemase'''. This enzyme participates in 4 [[metabolism|metabolic pathways]]: [[glycine]], [[serine]] and [[threonine]] metabolism, [[cysteine]] metabolism, D-[[glutamine]] and D-[[glutamate]] metabolism, and D-[[arginine]] and D-[[ornithine]] metabolism. It employs one [[cofactor (biochemistry)|cofactor]], [[pyridoxal phosphate]].

==Structural studies==

As of late 2007, 5 [[tertiary structure|structures]] have been solved for this class of enzymes, with [[Protein Data Bank|PDB]] accession codes {{PDB link|2FKP}}, {{PDB link|2GGG}}, {{PDB link|2GGH}}, {{PDB link|2GGI}}, and {{PDB link|2GGJ}}.

==References==
{{reflist|1}}
* {{cite journal |vauthors=Soda K, Osumi T | date = 1969 | title = Crystalline amino acid racemase with low substrate specificity | journal = Biochem. Biophys. Res. Commun. | volume = 35 | pages = 363–8 | pmid = 5788493 | doi = 10.1016/0006-291X(69)90507-5 | issue = 3 }}

{{Racemases and epimerases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}

[[Category:EC 5.1.1]]
[[Category:Pyridoxal phosphate enzymes]]
[[Category:Enzymes of known structure]]

{{isomerase-stub}}

Amino-acid racemase - Revision history

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