View source for Talk:Axon

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==An==
{{User:LinkBot/suggestions/Axon}}
An [[User:LinkBot|automated Wikipedia link suggester]] has some possible wiki link suggestions for the [[Axon]] article, and they have been placed on [[User:LinkBot/suggestions/Axon|this page]] for your convenience.<br />''Tip:'' Some people find it helpful if these suggestions are shown on this talk page, rather than on another page. To do this, just add <nowiki>{{User:LinkBot/suggestions/Axon}}</nowiki> to this page. &mdash; [[User:LinkBot|LinkBot]] 10:40, 17 Dec 2004 (UTC)

== Expansion / wikification ==

I can't believe this article is so sparse! Is anyone interested in a collaboration to expand and reference this article further as it's definately close to the "bread and butter" of Neuroscience. Also, is the disambig link really neccesary? I'm quite sure that "The Claws of Axos" aren't being confused for an obscure episode of Dr Who. <span style="font-size:10px; letter-spacing: 1.4px">[[User:JCraw|J O  R D A N]]</span>&nbsp;<sup><nowiki>[</nowiki>[[User talk:JCraw.|talk]]&nbsp;<nowiki>]</nowiki></sup> 15:53, 24 January 2008 (UTC)

== Passive Conduction ==
I'm looking for information on the passive flow of electrical current within an axon. Maybe we should consider adding a section for it. [[User:Paskari|Paskari]] ([[User talk:Paskari|talk]]) 13:01, 31 August 2008 (UTC)

== Bad Picture ==

The picture has the word "axon" and a line pointing to the division between the first myelin sheath and the dendrite.  Does anyone else think this is unclear?  The word "axon" should point to the whole axon, perhaps using a curly brace, or at least point to the middle of the axon.  I'll see what I can do to change it--let me know what you think.  [[User:Halberdo|Halberdo]] ([[User talk:Halberdo|talk]]) 22:16, 15 June 2009 (UTC)
:I think your change to [[Template:Neuron map]] is an improvement -- curly brackets or anything like that would probably just clutter it. [[User:Looie496|Looie496]] ([[User talk:Looie496|talk]]) 23:15, 15 June 2009 (UTC)

== Holomorphism ==

Hi! Is axon is holomorphic with flagellum?--[[User:MathFacts|MathFacts]] ([[User talk:MathFacts|talk]]) 08:40, 3 January 2010 (UTC)
:No, not even homeomorphic. [[User:Looie496|Looie496]] ([[User talk:Looie496|talk]]) 17:33, 3 January 2010 (UTC)
::Do neurons have flagellae? I read that photoreceptors have flagellae through which they conduct bimpulses, but what about other neurons?--[[User:MathFacts|MathFacts]] ([[User talk:MathFacts|talk]]) 13:41, 25 January 2010 (UTC)
:::My understanding is that a [[flagellum]] is a structure that waves back and forth.  I wasn't aware that photoreceptors have anything like that, and definitely most types of neurons do not.  They have [[dendrite]]s that can move, but more in the way that plants move than the way that animals move.  Axons are like dendrites in that they grow in the same sort of way that plants do.
::::No I meant a structure evolved from flagellum. It has a name but I cannot remember it now.--[[User:MathFacts|MathFacts]] ([[User talk:MathFacts|talk]]) 01:12, 27 January 2010 (UTC)

== Temperature sensitivity of afferent receptors at the ends of each fibre type ==

Is this worth putting in thermal thresholds, the temp. at which activity is seen in each fibre type? e.g.
:A-delta type 1: 53 degreesC
:A-delta type 2: 44 degreesC
:C-fibres:       43 degrees C

I can find the source of this if need be.
[[Special:Contributions/77.184.25.39|77.184.25.39]] ([[User talk:77.184.25.39|talk]]) 11:47, 17 January 2011 (UTC)
::That may be a bit specific for a general article on axons. Have you thought about [[Thermoreceptor]]? --[[User:Anthonyhcole|Anthonyhcole]] ([[User talk:Anthonyhcole|talk]]) 13:08, 17 January 2011 (UTC)

==Citations==
Under the injury heading, I followed the link (link# 16) to the citation that was provided for the statement that concussions are a mild form of diffuse axonal damage.  This citation does not suggest this to be so, and furthermore does not even mention axons.  I believe the current thought is it "may" be a mild form of DAI, but even the Cleveland Clinic has given conflicting reports on this statement.  <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/75.144.31.134|75.144.31.134]] ([[User talk:75.144.31.134|talk]]) 18:44, 20 June 2012 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->

== Student edits ==

I've seen a discussion about this page at [[WP:Education noticeboard]], and I am now placing this page on my watchlist. If there are any student edits (or any other edits for that matter) that fail to comply with Wikipedia policies and guidelines, revert, revert, revert! And for any students or faculty members working on the page, I hope that you will read [[Wikipedia:Assignments for student editors]]. --[[User:Tryptofish|Tryptofish]] ([[User talk:Tryptofish|talk]]) 22:01, 25 March 2013 (UTC)

== Orphaned references in [[:Axon]] ==

I check pages listed in [[:Category:Pages with incorrect ref formatting]] to try to fix reference errors. One of the things I do is look for content for [[User:AnomieBOT/docs/OrphanReferenceFixer|orphaned references]] in wikilinked articles. I have found content for some of [[:Axon]]'s orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for ''this'' article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.

<b>Reference named "Daniel":</b><ul>
<li>From [[Neural coding]]: {{cite journal  |vauthors=Butts DA, Weng C, Jin J, etal |title=Temporal precision in the neural code and the timescales of natural vision |journal=Nature |volume=449 |issue=7158 |pages=92–5 |date=September 2007 |pmid=17805296 |doi=10.1038/nature06105 |bibcode = 2007Natur.449...92B }}</li>
<li>From [[Myelin]]: {{cite journal | author = Hartline Daniel K | year = 2008 | title = What is myelin?. | url = | journal = Neuron Glia Biology | volume = 4 | issue = | pages = 153–163 | doi = 10.1017/S1740925X09990263 }}</li>
</ul>

I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. [[User:AnomieBOT|AnomieBOT]][[User talk:AnomieBOT|<span style="color:#880">⚡</span>]] 16:08, 19 February 2018 (UTC)

== Proposed Update of "Initial Segment" ==

In view of a large number of recent scientific articles about many aspects of the axon initial segment (AIS) and the giant ankyrin protein that organizes the AIS, I propose to update and expand this paragraph in hopes of providing an updated and more thorough multi-paragraph discussion.  If my efforts are productive, a separate article on the AIS might be justified--too soon to know. 

Comments or suggestions would be welcome.

[[User:EMIConscious|EMIConscious]] ([[User talk:EMIConscious|talk]]) 05:49, 17 June 2018 (UTC)

Right.

Here is a proposed new initial paragraph, which would precede (and require some edits in) the first sentence of the existing paragraph (footnotes to articles and links to other Wikipedia articles are shown in brackets):

"A typical neuron [link to Wikipedia article on Neuron] has an axon initial segment (AIS) that extends outward from the axon hillock [link to Wikipedia article on Axon hillock].  The AIS is different in both structure and function from other parts of the axon, and is sometimes referred to as a specialized compartment.  [footnote to Leterrier et al. 2017 Frontiers in Cell Neuroscience article]  One AIS function is to separate or provide a boundary between a neuron’s soma [link to Wikipedia article on Soma (biology)] or cell body and the main part of the neuron’s axon; another function is to generate and shape action potentials.  [footnote to Leterrier 2018]  Both of these functions support neuron cell polarity [link to Wikipedia article on Cell polarity], in which dendrites [link to Wikipedia article on Dendrite] (and, in some cases, soma) of a neuron receive input signals and the neuron’s axon provides output signals."

[[User:EMIConscious|EMIConscious]] ([[User talk:EMIConscious|talk]]) 19:33, 17 June 2018 (UTC)

:Thank you for seeking input in talk before making the edit! In my opinion, that looks very good, and you should feel free to go ahead and make the edit. If there are any small tweaks that need to be made, either I or someone else will do that after. I would suggest, though, omitting the "AIS" abbreviation. --[[User:Tryptofish|Tryptofish]] ([[User talk:Tryptofish|talk]]) 19:38, 17 June 2018 (UTC)

::Thanks for the input.  I have discovered additional relevant literature, and am therefore reworking my edit, but intend to go ahead and make it when complete.  [[User:EMIConscious|EMIConscious]] ([[User talk:EMIConscious|talk]]) 20:05, 23 June 2018 (UTC)

To Iztwoz and Tryptofish:  The two of you and I have recently been editing the "Initial Segment" section of the Axon article—thanks for your contributions.  As time permits, I intend to continue to edit and add material from recent scientific articles about the AIS, and perhaps you will continue to edit as well.  I have a few questions/responses:

—In view of the large amount of recent scientific literature about it, do you feel that the axon initial segment deserves a Wikipedia article of its own?

—It appears that Iztwoz asked on June 24 whether there are exceptions to each axon having an initial segment; I am not aware of a case in which a stable, healthy axon lacks an initial segment, but information is scanty about initial segments in the earliest axons (perhaps in our last common ancestor with lophotrochozoans and ecdysozoans?).

—One or both of you moved some material to the “Other animals” section.  In your view, is that also the appropriate place for information about evolution of the AIS throughout the bilaterians, as discussed in, e.g., Jegla et al., 2016, DOI: 10.1371.journal.pgen.1006457?

—I note that we have introduced both American and British usages.  What is the usual Wikipedia practice when this occurs?—Leave as is?  Change American usage to British? Or change British usage to American?

Cheers!

[[User:EMIConscious|EMIConscious]] ([[User talk:EMIConscious|talk]]) 04:53, 9 July 2018 (UTC)

:It was {{u|Iztwoz}} who made some of those changes, and I'll defer to his answers on some of that. You are right about the [[WP:ENGVAR]] issue, and I made an edit that I think takes care of that. About most of the rest of what you ask, I think that [[WP:DUE]] becomes important here. As a result, I'm reluctant to add much of anything more to this page about the AIS. I'm not strongly opposed to separating out a standalone page about it, but I'm not really convinced that it would be sufficiently [[WP:Notability|notable]] for that. One alternative to consider would be to add information about it to various existing pages. --[[User:Tryptofish|Tryptofish]] ([[User talk:Tryptofish|talk]]) 19:28, 9 July 2018 (UTC)
::A short answer - I'm on a break at the moment - I agree with the importance of the new information and I added a summarised edit. There is more that can be said it but it seems to me that this information can be held on this page. If anything does get too big then a split can be proposed. (Also the material was moved because it was not related to studies in the human). And I need to look at the Jegla article. Thanks --[[User:Iztwoz|Iztwoz]] ([[User talk:Iztwoz|talk]]) 10:39, 10 July 2018 (UTC)
:::Very late response - moved info back to AIS --[[User:Iztwoz|Iztwoz]] ([[User talk:Iztwoz|talk]]) 11:18, 11 December 2024 (UTC)

== "electrical impulses known as action potentials" is wrong and must be "electrical impulses caused by action potentials", ok? ==

cf. "that typically conducts electrical impulses known as action potentials", has to be "that typically conducts electrical impulses caused by action potentials": a electric current = electrons moving is caused because of a difference in Voltage potential. Any objections? Sincerely, [[User:SvenAERTS|SvenAERTS]] ([[User talk:SvenAERTS|talk]]) 12:58, 10 February 2020 (UTC)

== New view ==

It's too early to include, but we need to be ready to put in the view of axons as 'strings of pearls' when it has been properly vetted. https://scitechdaily.com/rewriting-biology-textbooks-johns-hopkins-scientists-debunk-century-old-assumption-about-brain-cells/ [[User:Kdammers|Kdammers]] ([[User talk:Kdammers|talk]]) 02:39, 10 December 2024 (UTC)