View source for Retrovirus direct repeat 1 (dr1)

{{Infobox rfam
| Name = Retrovirus direct repeat 1 (dr1)
| image = RF00214.jpg
| width =
| caption = Predicted [[secondary structure]] and [[sequence conservation]] of Retro_dr1
| Symbol = Retro_dr1
| AltSymbols =
| Rfam = RF00214
| miRBase =
| miRBase_family =
| RNA_type = [[Cis-regulatory element|Cis-reg]]
| Tax_domain = [[Virus]]es
| GO =
| SO = {{SO|0000233}}
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}

The '''direct repeat 1 (dr1) element''' is an [[cis-regulatory element|RNA element]] commonly found in the [[Three prime untranslated region|3' UTR]] of [[bird|Avian]] [[sarcoma]], [[Rous sarcoma virus|Rous sarcoma]] and [[Avian leukosis]] [[virus]]es ([[Alpharetrovirus]]es and Avian type C [[retroviruses]]). dr1 is required for efficient viral replication and is thought to be involved in [[genomic]] [[RNA]] packaging although this may not be its only role.<ref>{{cite journal | vauthors = Aschoff JM, Foster D, Coffin JM | title = Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect | journal = Journal of Virology | volume = 73 | issue = 9 | pages = 7421–7429 | date = September 1999 | doi = 10.1128/JVI.73.9.7421-7429.1999 | pmid = 10438832 | pmc = 104269 }}</ref>

== References ==
{{reflist}}

== External links ==
* {{Rfam|id=RF00214|name=Retrovirus direct repeat 1 (dr1)}}

[[Category:Cis-regulatory RNA elements]]
[[Category:Alpharetroviruses]]
{{molecular-cell-biology-stub}}