View source for Pyomyositis

{{Infobox medical condition (new)
| name            = Pyomyositis
| image           = Pyomyositis MRI.jpg
| caption         = Transverse T2 [[magnetic resonance imaging]] section through the hip region showing abscess collection in a patient with pyomyositis.
| synonyms        ='''Tropical pyomyositis''' or '''Myositis tropicans'''
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| diagnosis       = Diagnostic method used for PM includes ultrasound, CT scan and MRI. Ultrasound can be helpful in showing muscular heterogeneity or a purulent collection but it is not useful during the first stage of the disease. CT scan can confirm the diagnosis before abscesses occur with enlargement of the involved muscles and hypodensity when abscess is present, terogenous attenuation and fluid collection with rim enhancement can be found. MRI is useful to assess PM and determine its localization and extension
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'''Pyomyositis''' is a [[bacteria]]l [[infection]] of the [[skeletal muscle]]s which results in an [[abscess]]. Pyomyositis is most common in [[tropical]] areas but can also occur in [[temperate zone]]s.

Pyomyositis can be classified as primary or secondary. Primary pyomyositis is a skeletal muscle infection arising from hematogenous infection, whereas secondary pyomyositis arises from localized penetrating trauma or contiguous spread to the muscle.<ref>{{cite web |title=Primary pyomyositis |url=https://www.uptodate.com/contents/primary-pyomyositis |website=UpToDate |access-date=6 March 2023}}</ref>

==Diagnosis==
Diagnosis is done via the following manner:{{cn|date=June 2021}}
* Pus discharge culture and sensitivity
* X ray of the part to rule out osteomyelitis
* Creatinine phosphokinase (more than 50,000 units)
* MRI is useful
* Ultrasound guided aspiration

==Treatment==
The abscesses within the muscle must be drained [[surgery|surgically]] (not all patients require surgery if there is no abscess). [[Antibiotics]] are given for a minimum of three weeks to clear the infection.<ref name="pmid16983604"/>

==Epidemiology==
Pyomyositis is most often caused by the bacterium ''[[Staphylococcus aureus]]''.<ref name="pmid15138315">{{cite journal |vauthors=Chauhan S, Jain S, Varma S, Chauhan SS | title = Tropical pyomyositis (myositis tropicans): current perspective | journal = Postgrad Med J | volume = 80| issue = 943 | pages = 267–70 | year = 2004| pmid = 15138315 | doi = 10.1136/pgmj.2003.009274| url=http://pmj.bmjjournals.com/cgi/pmidlookup?view=long&pmid=15138315 | pmc = 1743005}}</ref> The infection can affect any skeletal muscle, but most often infects the large muscle groups such as the [[quadriceps]] or [[gluteal muscles]].<ref name="pmid16983604">{{cite journal| vauthors = Pannaraj PS, Hulten KG, Gonzalez BE, ((Mason EO Jr)), Kaplan SL| title = Clin Infect Dis| year = 2006| volume = 43| pages = 953–60| pmid = 16983604| issue = 8| doi = 10.1086/507637| journal = Clinical Infectious Diseases| doi-access = free}}</ref><ref name="pmid17273045">{{cite journal| author = Ovadia D| title = Primary pyomyositis in children: a retrospective analysis of 11 cases| journal = J Pediatr Orthop B| year = 2007| volume = 16| issue = 2| pages = 153–159| pmid = 17273045|name-list-style=vanc| author2 = Ezra E| author3 = Ben-Sira L| display-authors = 3| doi = 10.1097/BPB.0b013e3280140548| last4 = Kessler| first4 = A| last5 = Bickels| first5 = J| last6 = Keret| first6 = D| last7 = Yaniv| first7 = M| last8 = Wientroub| first8 = S| last9 = Lokiec| first9 = F}}</ref><ref name="pmid19944229">{{cite journal| author = Mitsionis GI| title = Pyomyositis in children: early diagnosis and treatment| journal = J Pediatr Surg| year = 2009| volume = 44| issue = 11| pages = 2173–178| pmid = 19944229|name-list-style=vanc| author2 = Manoudis GN| author3 = Lykissas MG| display-authors = 3| doi = 10.1016/j.jpedsurg.2009.02.053| last4 = Sionti| first4 = I| last5 = Motsis| first5 = E| last6 = Georgoulis| first6 = AD| last7 = Berisa| first7 = AE}}</ref>

Pyomyositis is mainly a disease of children and was first described by Scriba in 1885. Most patients are aged 2 to 5 years, but infection may occur in any age group.<ref>{{cite journal|vauthors=Small LN, Ross JJ | title = Tropical and temperate pyomyositis| journal = Infect Dis Clin North Am| year = 2005| volume = 19| pages = 981–989| doi = 10.1016/j.idc.2005.08.003| pmid = 16297743| issue = 4}}</ref><ref name="pmid19013093">{{cite journal|vauthors=Taksande A, Vilhekar K, Gupta S | title = Primary pyomyositis in a child| journal = Int J Infect Dis| year = 2009| volume = 13| pages = e149–e151| pmid = 19013093| doi = 10.1016/j.ijid.2008.08.013| issue = 4| doi-access = free}}</ref> Infection often follows minor trauma and is more common in the tropics, where it accounts for 4% of all hospital admissions. In temperate countries such as the US, pyomyositis was a rare condition (accounting for 1 in 3000 pediatric admissions), but has become more common since the appearance of the [[ST8:USA300|USA300]] strain of [[Methicillin-resistant Staphylococcus aureus|MRSA]].<ref name="pmid16983604"/><ref name="pmid17273045"/><ref name="pmid19944229"/>

Gonococcal pyomyositis is a rare infection caused by ''[[Neisseria gonorrhoeae]]''.<ref name="pmid33294370">{{cite journal |vauthors=Jensen M |title=Neisseria gonorrhoeae pyomyositis complicated by compartment syndrome: A rare manifestation of disseminated gonococcal infection |journal=IDCases |volume=23 |issue= |pages=e00985 |date=2021 |pmid=33294370 |pmc=7695882 |doi=10.1016/j.idcr.2020.e00985 |url=}}</ref>

==Additional images==
<gallery widths="300px" heights="200px"> 
File:CT pyomyositis.jpg|CT with IV contrast showing enlargement and heterogeneous hypodensity in the right pectoralis major muscle.  A focal abscess collection with gas within it is present medially.  There are enlarged axillary lymph nodes and some extension into the right hemithorax.  Note the soft tissue and phlegmon surrounding the right internal mammary artery and vein.  The patient was HIV+ and the pyomyositis is believed to be due to direct inoculation of the muscle related to parenteral drug abuse. The patient admitted to being a "pocket shooter"
File:Tropical pyomyositis CT.JPG|CT exam showing a multiloculated fluid collection in the left gluteus minimus muscle found to be a staph aureus pyomyositis in a 12-year-old healthy boy.
File:Axial T1 FS Post Gad tropical pyomyositis.JPG|Axial T1 weighted fat suppressed post IV gadolinium contrast enhanced MRI image showing a mutliloculated bacterial abscess in the left gluteal muscle which grew ''Staphylococcus aureus'' (methicillin sensitive) thought to be due to tropical pyomyositis.
File:Cor post gad MRI Tropical pyomyositis.JPG|Coronal fat suppressed post contrast image showing a multiloculated bacterial abscess in the left gluteus minimus muscle due to tropical pyomyositis.
File:Cor T2 MRI tropical pyomyositis.JPG|Coronal T2 weighted fat suppressed image showing a multiloculated fluid collection in the left gluteal musculature due to tropical pyomositis in a 12-year-old boy.
</gallery>
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== References ==
{{reflist}}
*Maravelas R, Melgar TA, Vos D, Lima N, Sadarangani S (2020). "Pyomyositis in the United States 2002-2014". J Infect. 80(5):497-503. doi:10.1016/j.jinf.2020.02.005. {{PMID|32147332}}.

== External links ==
{{Medical resources
| DiseasesDB      = 29474
| ICD10           = {{ICD10|M|60|0|m|60}}
| ICD9            = {{ICD9|040.81}}, {{ICD9|728.0}}
| ICDO            =
| OMIM            =
| MedlinePlus     =
| eMedicineSubj   =
| eMedicineTopic  =
| MeshID          = D052880
| Orphanet        = 764
| SNOMED CT       = 65110003
}}
{{Bacterial diseases}}
{{Myopathy}}
{{Bacterial cutaneous infections}}

[[Category:Bacterial diseases]]
[[Category:Bacterium-related cutaneous conditions]]
[[Category:Muscular disorders]]
[[Category:Inflammations]]