View source for Mycobacterium xenopi

{{Short description|Species of bacterium}}

{{Speciesbox	
| taxon = Mycobacterium xenopi
| authority = Schwabacher 1959, ATCC 19250
}}

'''''Mycobacterium xenopi''''' is a slow-growing [[scotochromogenic]] species of ''[[Mycobacterium]]''. It was first reported by Schwabacher<ref>{{cite journal |doi=10.1017/S0022172400019896 |pmid=13641655 |pmc=2218100 |title=A strain of mycobacterium isolated from skin lesions of a cold-blooded animal, Xenopus laevis, and its relation to atypical acid-fast bacilli occurring in man |journal=Journal of Hygiene |volume=57 |issue=1 |pages=57–67 |year=2009 |last1=Schwabacher |first1=Herta }}</ref> in 1959, having been isolated in [[lesion]]s found on a ''[[Xenopus laevis]]'', but the possibility of human infection was not confirmed until 1965. It has been cultured from hot and cold water taps, hospital hot water generators and storage tanks, and other environmental sources. 

It has low [[pathogenicity]] in humans,<ref>{{EMedicine|article|223480|Mycobacterium Xenopi}}</ref> and where infections have been found they are closely associated with [[immunocompromised]] individuals, such as an extrapulmonary malignancy, alcoholism, diabetes mellitus, or immunosuppressive therapy. Pulmonary disease may be chronic, subacute, or acute; symptoms are indistinguishable from those associated with disease caused by ''M. kansasii''.

Radiographic findings with ''M. xenopi'' pulmonary disease are variable but most often include upper lobe cavitary abnormalities similar to tuberculosis.

Treatment is usually with macrolide, rifampin, and ethambutol with moxifloxacin.

[[Biological type|Type strain]]: strain [[American Type Culture Collection|ATCC]] 19250 = CCUG 28011 = CCUG 31306 = CIP 104035 = DSM 43995 = NCTC 10042.

==References==
{{Reflist}}

==Further reading==
*{{cite journal |doi=10.1099/00207713-30-1-225 |title=Approved Lists of Bacterial Names |journal=International Journal of Systematic Bacteriology |volume=30 |issue=1 |pages=225–420 |year=1980 |last1=Skerman |first1=V. B. D. |last2=McGowan |first2=V. |last3=Sneath |first3=P. H. A. |doi-access=free }}

==External links==
*[http://bacdive.dsmz.de/index.php?search=8370&submit=Search Type strain of ''Mycobacterium xenopi'' at Bac''Dive'' -  the Bacterial Diversity Metadatabase]

{{Mycobacteria}}
{{Gram-positive bacterial diseases}}
{{Taxonbar|from=Q4044724}}

[[Category:Acid-fast bacilli]]
[[Category:Nontuberculous mycobacteria|xenopi]]
[[Category:Bacteria described in 1959]]


{{Mycobacterium-stub}}