View source for I-SMAD

{{Short description|Inhibitory SMAD proteins}}
'''I-SMAD or Inhibitor SMAD''' is a subclass of [[SMAD (protein)|SMAD]]s that are involved in the modulation of [[transforming growth factor beta]] [[ligands]]. This class includes [[mothers against decapentaplegic homolog 6|SMAD6]] and [[mothers against decapentaplegic homolog 7|SMAD7]]. They compete with [[mothers against decapentaplegic homolog 4|SMAD4]] and consequently regulate the transcription of its gene products.

==See also==
* [[SMAD (protein)]]
* [[R-SMAD]]
==External links==
* {{MeshName|I-Smad+Proteins}}

{{TGF beta signaling}}
{{Transcription factors|g1}}
{{TGFβ receptor superfamily modulators}}

{{molecular-cell-biology-stub}}

[[Category:SMAD (protein)]]

[[Category:Transcription factors]]