View source for EPA list of extremely hazardous substances

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This is the '''list of extremely hazardous substances''' defined in Section 302 of the U.S. [[Emergency Planning and Community Right-to-Know Act]] ({{UnitedStatesCode|42|11002}}). The list can be found as an appendix to {{CodeFedReg|40|355}}.<ref>[https://www.ecfr.gov/current/title-40/chapter-I/subchapter-J/part-355#Appendix-A-to-Part-355 Appendix A to Part 355 - The List of Extremely Hazardous Substances and Their Threshold Planning Quantities] in the Code of Federal Regulations</ref>  Updates as of 2006 can be seen on the Federal Register, {{Federal Register|71|47121}} (August 16, 2006).<ref>[http://www.gpo.gov/fdsys/pkg/FR-2006-08-16/pdf/E6-13491.pdf#page=16 Federal Register 71 FR 47121 (amendment, August 16, 2006)]</ref>

The data were provided by the [[United States Environmental Protection Agency]] (EPA). 

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{{compact ToC|side=yes|top=yes|num=yes}}

== A ==
* [[Acetone cyanohydrin]]
* [[Acetone thiosemicarbazide]]
* [[Acrolein]]
* [[Acrylamide]]
* [[Acrylonitrile]]
* [[Acryloyl chloride]]
* [[Adiponitrile]]
* [[Aldicarb]]
* [[Aldrin]]
* [[Allyl alcohol]]
* [[Allylamine]]
* [[Aluminum phosphide]]
* [[Aminopterin]]
* [[Amiton]]
* [[Amiton oxalate]]
* [[Ammonia]]
* [[Amphetamine]]
* [[Aniline]]
* [[Aniline, 2,4,6-trimethyl-]]
* [[Antimony pentafluoride]]
* [[Antimycin A]]
* ANTU ([[Alpha-Naphthylthiourea]])
* [[Arsenic pentoxide]]
* [[Arsenous oxide]]
* [[Arsenous trichloride]]
* [[Arsine]]
* [[Azinphos-ethyl]]
* [[Azinphos-methyl]]

== B ==
* [[Benzal chloride]]
* [[Benzenamine, 3-(trifluoromethyl)-]]
* [[Benzenearsonic acid]]
* [[Benzimidazole, 4,5-dichloro-2-(trifluoromethyl)-]]
* [[Benzotrichloride]]
* [[Benzyl chloride]]
* [[Benzyl cyanide]]
* [[Bicyclo(2.2.1)heptane-2-carbonitrile]]
* [[Bis(chloromethyl) ketone]]
* [[Bitoscanate]]
* [[Boron trichloride]]
* [[Boron trifluoride]]
* [[Boron trifluoride]] compound with [[dimethyl ether]] (1:1)
* [[Bromadiolone]]
* [[Bromine]]

== C ==
* [[Cadmium oxide]]
* [[Cadmium stearate]]
* [[Calcium arsenate]]
* [[Camphechlor]]
* [[Cantharidin]]
* [[Carbachol chloride]]
* [[Tirpate|Carbamic acid, Methyl-, O-(((2,4-Dimethyl-1,3-Dithiolan-2-yl)Methylene)Amino)-]] (Tirpate)
* [[Carbofuran]]
* [[Carbon disulfide]]
* [[Carbophenothion]]
* [[Chlordane]]
* [[Chlorfenvinfos]]
* [[Chlorine]]
* [[Chlormephos]]
* [[Chlormequat chloride]]
* [[Chloroacetic acid]]
* [[2-chloroethanol]]
* [[Chloroethyl chloroformate]]
* [[Chloroform]]
* [[Chloromethyl ether]]
* [[Chloromethyl methyl ether]]
* [[Chlorophacinone]]
* [[Chloroxuron]]
* [[Chlorthiophos]]
* [[Chromic chloride]]
* [[Cobalt carbonyl]]
* [[Colchicine]]
* [[Coumaphos]]
* [[Cresol, -o]]
* [[Crimidine]]
* [[Crotonaldehyde]]
* [[Crotonaldehyde, (E)-]]
* [[Cyanogen bromide]]
* [[Cyanogen iodide]]
* [[Cyanophos]]
* [[Cyanuric fluoride]]
* [[Cycloheximide]]
* [[Cyclohexylamine]]

== D ==
* [[Decaborane(14)]]
* [[Demeton]]
* [[Demeton-S-methyl]]
* [[Dialifor]]
* [[Diborane]]
* [[Dichloroethyl ether]]
* [[Dichloromethylphenylsilane]]
* [[Dichlorvos]]
* [[Dicrotophos]]
* [[Diepoxybutane]]
* [[Diethyl chlorophosphate]]
* [[Digitoxin]]
* [[Diglycidyl ether]]
* [[Digoxin]]
* [[Dimefox]]
* [[Dimethoate]]
* [[Dimethyl phosphorochloridothioate]]
* [[Dimethyl-p-phenylenediamine]]
* [[Dimethyldichlorosilane]]
* [[Dimethylhydrazine]]
* [[Dimetilan]]
* [[Dinitrocresol]]
* [[2,4-Dinitrophenol]]
* [[Dinoseb]]
* [[Dinoterb]]
* [[Dioxathion]]
* [[Diphacinone]]
* [[Disulfoton]]
* [[Dithiazanine iodide]]
* [[Dithiobiuret]]

== E ==
* [[Endosulfan]]
* [[Endothion]]
* [[Endrin]]
* [[Epichlorohydrin]]
* [[O-Ethyl-O-(4-nitrophenyl)phenylthiophosphonate|EPN]], or [[O-Ethyl-O-(4-nitrophenyl)phenylthiophosphonate]]
* [[Ergocalciferol]]
* [[Ergotamine tartrate]]
* [[Ethanesulfonyl chloride, 2-chloro-]]
* [[Ethanol, 1,2-dichloro-, acetate]]
* [[Ethion]]
* [[Ethoprophos]]
* [[Ethylbis(2-chloroethyl)amine]]
* [[Ethylene fluorohydrin]]
* [[Ethylene oxide]]
* [[Ethylenediamine]]
* [[Ethyleneimine]]
* [[Ethylthiocyanate]]

== F ==
* [[Fenamiphos]]
* [[Fenitrothion]]
* [[Fensulfothion]]
* [[Fluenetil]]
*[[Fluomine]]
* [[Fluorine]]
* [[Fluoroacetamide]]
* [[Fluoroacetic acid]]
* [[Fluoroacetyl chloride]]
* [[Fluorouracil]]
* [[Fonofos]]
* [[Formaldehyde]]
* [[Formaldehyde cyanohydrin]]
* [[Formetanate hydrochloride]]
* [[Formothion]]
* [[Formparanate]]
* [[Fosthietan]]
* [[Fuberidazole]]
* [[Furan]]

== G ==
* [[Gallium trichloride]]

== H ==
* [[Hexachlorocyclopentadiene]]
* [[N,N'-Dibutylhexamethylenediamine|Hexamethylenediamine, N,N'-dibutyl-]]
* [[Hydrazine]]
* [[Hydrocyanic acid]]
* [[Hydrogen chloride]] (gas only)
* [[Hydrogen fluoride]]
* [[Hydrogen peroxide]] (conc > 52%)
* [[Hydrogen selenide]]
* [[Hydrogen sulfide]]
* [[Hydroquinone]]

== I ==
* [[Iron pentacarbonyl]]
* [[Isobenzan]]
* [[Isocyanic acid, 3,4-dichlorophenyl ester]]
* [[Isodrin]]
* [[Isophorone diisocyanate]]
* [[Isopropylmethylpyrazolyl dimethylcarbamate]]

== L ==
* [[Lactonitrile]]
* [[Leptophos]]
* [[Lewisite]]
* [[Lindane]]
* [[Lithium hydride]]

== M ==
* [[Malononitrile]]
* [[Methylcyclopentadienyl manganese tricarbonyl|Manganese, tricarbonyl methylcyclopentadienyl]]
* [[Mechlorethamine]]
* [[Mercuric acetate]]
* [[Mercuric chloride]]
* [[Mercuric oxide]]
* [[Methacrolein diacetate]]
* [[Methacrylic anhydride]]
* [[Methacrylonitrile]]
* [[Methacryloyl chloride]]
* [[Methacryloyloxyethyl isocyanate]]
* [[Methamidophos]]
* [[Methanesulfonyl fluoride]]
* [[Methidathion]]
* [[Methiocarb]]
* [[Methomyl]]
* [[Methoxyethylmercuric acetate]]
* [[Methyl 2-chloroacrylate]]
* [[Methyl bromide]]
* [[Methyl chloroformate]]
* [[Methyl hydrazine]]
* [[Methyl isocyanate]]
* [[Methyl isothiocyanate]]
* [[Methyl phenkapton]]
* [[Methyl phosphonic dichloride]]
* [[Methyl thiocyanate]]
* [[Methyl vinyl ketone]]
* [[Methylmercuric dicyanamide]]
* [[Methyltrichlorosilane]]
* [[Metolcarb]]
* [[Mevinphos]]
* [[Mexacarbate]]
* [[Mitomycin C]]
* [[Monocrotophos]]
* [[Muscimol]]
* [[Mustard gas]]

== N ==
* [[Nickel carbonyl]]
* [[Nicotine]]
* [[Nicotine sulfate]]
* [[Nitric oxide]]
* [[Nitrobenzene]]
* [[Nitrocyclohexane]]
* [[Nitrogen dioxide]]
* [[N-Nitrosodimethylamine|''N''-Nitrosodimethylamine]]
* [[Norbormide]]

== O ==
* [[Organorhodium complex]]
* [[Ouabain]]
* [[Oxamyl]]
* [[Oxetane, 3,3-bis(chloromethyl)-]]
* [[Oxydisulfoton]]

== P ==
* [[Paraquat]]
* [[Paraquat methosulfate]]
* [[Parathion]]
* [[Parathion-methyl]]
* [[Paris green]]
* [[Pentaborane]]
* [[Pentadecylamine]]
* [[Peracetic acid]]
* [[Perchloromethylmercaptan]]
* [[Phenol]]
* [[Phenol, 2,2'-thiobis(4-chloro-6-methyl)-]]
* [[Phenol, 3-(1-methylethyl)-, methylcarbamate]]
* [[Phenoxarsine, 10,10'-oxydi-]]
* [[Phenyl dichloroarsine]]
* [[Phenylhydrazine hydrochloride]]
* [[Phenylmercury acetate]]
* [[Phenylsilatrane]]
* [[Phenylthiourea]]
* [[Phosacetim]]
* [[Phosfolan]]
* [[Phosgene]]
* [[Phosmet]]
* [[Phosphamidon]]
* [[Phosphine]]
* [[Phosphonothioic acid, methyl-, O-ethyl O-(4-(methylthio)phenyl) ester]] <!-- CAS# 2703-13-1 -->
* [[Phosphonothioic acid, methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester]] <!-- CAS# 50782-69-9 VX -->
* [[Phosphonothioic acid, methyl-, O-(4-nitrophenyl) O-phenyl ester]] <!-- CAS# 2665-30-7 -->
* [[Phosphoric acid, dimethyl 4-(methylthio)phenyl ester]] <!-- CAS# 3254-63-5 -->
* [[Phosphonothioic acid, O,O-dimethyl-S-(2-methylthio) ethyl ester]] <!-- 2587-90-8 -->
* [[Phosphorus]]
* [[Phosphorus oxychloride]]
* [[Phosphorus pentachloride]]
* [[Phosphorus trichloride]]
* [[Physostigmine]]
* [[Physostigmine]], [[salicylate]] (1:1)
* [[Picrotoxin]]
* [[Piperidine]]
* [[Pirimifos-ethyl]]
* [[Plutonium]]
* [[Polonium-210]]
* [[Potassium arsenite]]
* [[Potassium cyanide]]
* [[Potassium silver cyanide]]
* [[Promecarb]]
* [[Propargyl bromide]]
* [[Propionitrile]]
* [[Propionitrile, 3-chloro-]]
* [[Propiophenone, 4'-amino-]]
* [[Propyleneimine]]
* [[Prothoate]]
* [[Pyrene]]
* [[Pyridine, 4-amino-]]
* [[Pyridine, 4-nitro-, 1-oxide]]
* [[Pyriminil]]

== R ==
* [[Ricin]]

== S ==
* [[Salcomine]]
* [[Sarin]]
* [[Selenious acid]]
* [[Semicarbazide hydrochloride]]
* [[Silane, (4-aminobutyl)diethoxymethyl-]]
* [[Sodium arsenate]]
* [[Sodium azide]]
* [[Sodium cacodylate]]
* [[Sodium cyanide]]
* [[Sodium fluoroacetate]]
* [[Sodium pentachlorophenate]]
* [[Sodium selenate]]
* [[Sodium selenite]]
* [[Stannane, acetoxytriphenyl-]]
* [[Strychnine]]
* [[Strychnine sulfate]]
* [[Sulfotep]]
* [[Sulfoxide, 3-chloropropyl octyl]]
* [[Sulfur dioxide]]
* [[Sulfur tetrafluoride]]
* [[Sulfur trioxide]]
* [[Sulfuric acid]]

== T ==
* [[Tabun (nerve agent)|Tabun]]
* [[Tellurium]]
* [[Tellurium hexafluoride]]
* [[TEPP]]
* [[Terbufos]]
* [[Tetraethyllead]]
* [[Tetraethyltin]]
* [[Tetranitromethane]]
* [[Thallium sulfate]]
* [[Thallous carbonate]]
* [[Thallous chloride]]
* [[Thallous malonate]]
* [[Thallous sulfate]]
* [[Thiocarbazide]]
* [[Thiofanox]]
* [[Thionazin]]
* [[Thiophenol]]
* [[Thiosemicarbazide]]
* [[Thiourea, (2-chlorophenyl)-]]
* [[Thiourea, (2-methylphenyl)-]]
* [[Titanium tetrachloride]]
* [[Toluene 2,4-diisocyanate]]
* [[Toluene 2,6-diisocyanate]]
* [[Trans-1,4-dichlorobutene]]
* [[Triamiphos]]
* [[Triazofos]]
* [[Trichloro(chloromethyl)silane]]
* [[Trichloro(dichlorophenyl)silane]]
* [[Trichloroacetyl chloride]]
* [[Trichloroethylsilane]]
* [[Trichloronate]]
* [[Trichlorophenylsilane]]
* [[Triethoxysilane]]
* [[Trimethylchlorosilane]]
* [[Trimethylolpropane phosphite]]
* [[Trimethyltin chloride]]
* [[Triphenyltin chloride]]
* [[Tris(2-chloroethyl)amine]]

== V ==
* [[Valinomycin]]
* [[Vinyl acetate monomer]]

== W ==
* [[Warfarin]]
* [[Warfarin sodium]]

== X ==
* [[Xylylene dichloride]]

== Z ==
* [[Zinc phosphide]]

== See also ==
* [[List of highly toxic gases]]

== References ==

{{reflist}}
* {{citation | publisher = [[United States Government Publishing Office|Government Printing Office]] | title = 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities | url = http://edocket.access.gpo.gov/cfr_2008/julqtr/pdf/40cfr355AppA.pdf | edition = July 1, 2008 | access-date = March 8, 2009 | archive-url = https://web.archive.org/web/20120225051612/http://edocket.access.gpo.gov/cfr_2008/julqtr/pdf/40cfr355AppA.pdf | archive-date = 2012-02-25 | url-status = dead }}

{{Toxicology}}

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[[Category:United States Environmental Protection Agency]]
[[Category:Poisons]]
[[Category:Chemical compounds]]
[[Category:Chemistry-related lists|Extremely hazardous substances]]
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