View source for BCP-1 cells

{{short description|Cell line}}
'''BCP-1 cells''' are a clonal lymphoma cell line. They were derived from the peripheral blood mononuclear cells of an [[HIV]] seronegative patient with a body cavity based [[primary effusion lymphoma]] (PEL). BCP-1 cells are positive for [[Kaposi's sarcoma-associated herpesvirus|KSHV]], but negative for [[Epstein–Barr virus|EBV]]. The cell line is used extensively for KSHV serologic assays and epidemiologic studies as well as other KSHV laboratory studies such as KSHV reactivation from latency with TPA or ectopic expression of KSHV ORF 50. BCP-1 has been deposited to ATCC by the creators for public use in research: https://web.archive.org/web/20070929090610/http://www.atcc.org/common/catalog/numSearch/numResults.cfm?atccNum=CRL-2294.

==References and notes==
{{reflist}}
*{{cite journal | vauthors = Gao SJ, Kingsley L, Li M, Zheng W, Parravicini C, Ziegler J, Newton R, Rinaldo CR, Saah A, Phair J, Detels R, Chang Y, Moore PS | title = KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. | journal = Nat. Med. | year = 1996 | volume = 2 | issue = 8 | pages = 925–8 | pmid = 8705864 | doi=10.1038/nm0896-925| s2cid = 10275045 }}
*{{cite journal | vauthors = Boshoff C, Gao SJ, Healy LE, Matthews S, Thomas AJ, Coignet L, Warnke RA, Strauchen JA, Matutes E, Kamel OW, Moore PS, Weiss RA, Chang Y | title = Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice. | journal = Blood | year = 1998 | volume = 91 | issue = 5 | pages = 1671–9 | doi = 10.1182/blood.V91.5.1671 | pmid = 9473233| doi-access = free }}

==External links==
*[http://www.cellosaurus.org/CVCL_0107 Cellosaurus entry for BCP-1]

[[Category:Virology]]
[[Category:Human cell lines]]
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