YSC
YSC may refer to:
Acronyms and initialisms
- Yemeni Super Cup
- Yerevan Komitas State Conservatory a conservatory located in Yerevan, Armenia
- Yugoslav Super Cup
- Young Survival Coalition an international group for women under 40 who have been diagnosed with breast cancer
- Youth detention center#Youth Services Center the District of Columbia's secure juvenile detention center
Codes
- Sherbrooke Airport has IATA code YSC
- Jassic dialect has ISO 639-3 code ysc