Tolazoline
Template:Short description Template:Drugbox
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.[1] It is a vasodilator that is used to treat spasms of peripheral blood vessels (as in acrocyanosis). It has also been used (in conjunction with sodium nitroprusside) successfully as an antidote to reverse the severe peripheral vasoconstriction which can occur as a result of overdose with certain 5-HT2A receptor agonist drugs such as 25I-NBOMe,[2] DOB, and Bromodragonfly.[3][4]
It is however most commonly used in veterinary medicine, to reverse xylazine-induced sedation.[5][6]
References
Template:Peripheral vasodilators Template:Topical products for joint and muscular pain Template:Adrenergic receptor modulators