Talk:Bromocriptine

Template:WikiProject banner shell Template:Reliable sources for medical articles I think this page is miscategorized. Hypogonadism is not "feminism-related" or "Female-related".

I agree. Men can suffer with pituitary disease and Parkinson's disease.

I added the information related to cocaine abuse. Although mitigation of cocaine addiction is not a current indication for bromocriptine I felt it very relevant to the page and added some links referring to the ongoing research in that area. --BroodGimp 20:49, 14 January 2006 (UTC)

Feel free to erase my comment, if it's not supposed to go here. Do medication articles list if it's over the counter or prescription in most countries?

Irreversible dopaminergic agonist?

It's mentioned as a functionally irreversible agonist, but maybe has something to do with covalent bonding like oxymorphazone does for the mu-receptor only on the dopamine system?

"The ability of the dopamine receptor antagonist spiperone [749-02-0] to block dopamine [51-61-6]- or bromocriptine (I) [25614-03-3]- inhibited prolactin [9002-62-4] release from dispersed rap anterior pituitary cells was tested in vitro. In a continuously perfused cell column app., spiperone rapidly counteracted the inhibitory effect of dopamine but was unable to reverse the inhibitory effect of I when added 30 min after I. However, spiperone completely blocked the action of I if added simultaneously with I. These basic data were confirmed, and the time relations more accurately defined, in static incubations of monolayer culture. Spiperone blocked the typical inhibition of prolactin release by I only if the cells were pre- or coincubated with the antagonist. If spiperone was added as soon as 1 min after I, the antagonist was unable to block the complete expression of the I inhibition. Evidently, I is a functionally irreversible dopamine agonist for at least the 4 h of these studies." source: European Journal of Pharmacology 1984, 99(1), p.85 Nagelfar (talk) 19:03, 20 October 2008 (UTC)

Subtle Vandalism?

"two peptide groups of its tripeptide moiety (shown in black at the upper left of the Figure) are crosslinked with Meagan Haases, forming the >N-C(OH)< juncture between the two rings with the amide functionality"

I'm not sure who or what Meagan Haases is but I'm fairly confident it has nothing to do with peptide linkages. I don't know enough about this class of compounds to be able to change that into something appropriate. 174.23.200.137 (talk) 14:30, 19 June 2010 (UTC)

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bromocriptine

drug — Preceding unsigned comment added by 156.203.158.112 (talk) 18:15, 6 April 2019 (UTC)